Protein synthesis is the process that the cell goes through to make a protein from the information stored in the DNA. The video below shows a demonstration that you can do in your classroom to show how protein synthesis works. This demonstration emphasizes the following points:

1. DNA contains the information to make a specific protein.
2. The DNA is in the nucleus of the cell.
3. The DNA cannot leave the nucleus.
4. The ribosomes make the protein from the information.
5. The ribosomes are in the cytoplasm and cannot go into the nucleus.

The metaphor that I use in class is that the DNA is like a series of recipe books in the library. These books cannot be checked out/taken out of the library. The only way to get the information that is in the books out of the library is to make a copy. mRNA is the copy of the information that can leave the nucleus and go into the cytoplasm so that the ribosome can read and make the protein. Watch the video to see how it comes all together.

Teaching tips: Place the amino acids around the classroom (cytoplasm). Assign students to be specific tRNA’s. They will get the specific amino acid and bring it to the ribosome for you.